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Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors

In stacks Glow Blend et Klow Wolverine, it provides the "extracellular matrix" dimension which complements angiogenesis (BPC-157) and cell migration (TB-500) (Pickart & Margolina, Int J Mol Sci 2018)

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Key publications: 'Stimulation of collagen synthesis in fibroblast cultures by GHK-Cu' (1988, FEBS Letters), 'In vivo stimulation of connective tissue accumulation by GHK-Cu' (1993), 'GHK-Cu stimulates matrix metalloproteinase-2 expression' (2000)